Salivary Immunoglobulin A responses to 6-minute walk test in elderly women


  • Iván Rentería Autonomous University of Baja California, Mexico
  • Patricia Concepción García Suarez Autonomous University of Baja California, Mexico
  • Ermilo Cantón Martínez Autonomous University of Baja California, Mexico
  • Peter Grandjean Baylor University, United States
  • Alberto Jiménez Maldonado Autonomous University of Baja California, Mexico



6 Minute Walk Test, Blood lactate, Elderly women, Secretory immunoglobulin A


Objetive: The aim of the present study was evaluate the effect of the 6-minute walk test (6MWT) on the secretory immunoglobulin A (sIgA) kinetics in whole saliva of healthy elderly women. Methods: Nine healthy, elderly females (age 61 ± 6.7 years) performed the 6 MWT. Saliva samples and heart rate (HR) were measured in basal, immediately (IPE), and 30 minutes after the 6 MWT (30-Post Ex). Blood lactate [La] was measured at the same intervals. The ELISA assay was used to determine the sIgA concentrations [sIgA]. The Biuret assay was employed to determine the total proteins levels in saliva. Results: The exercise intensity reached by the participants was ≈ 84 + 16% of maximum HR. Baseline [La] was 1.8 ± 0.9 mmol/L. [La] at IPE increased 3.4 mmol/L above baseline (p = 0.02). [sIgA] increased by 233.3 + 109.3 % at IPE and remained 211.2 + 100.1 % greater at 30-Post Ex compared with basal (p = 0.02). The 6 MWT did not modify total proteins levels (p > 0.05). Conclusion: The 6 MWT, performed to submaximal intensity, appears to be enough of a stimulus to increases sIgA levels in healthy elderly women independent of total proteins concentration in saliva.


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How to Cite

Rentería, I., García Suarez, P. C., Cantón Martínez, E., Grandjean, P., & Jiménez Maldonado, A. (2019). Salivary Immunoglobulin A responses to 6-minute walk test in elderly women. Journal of Human Sport and Exercise, 14(1), 225–235.



Sport Medicine, Nutrition & Health