Physical activity has numerous beneficial effects on metabolic and inflammatory processes


  • Rita Polito University of Foggia, Italy
  • Vincenzo Monda University of Campania Luigi Vanvitelli, Italy
  • Alberto Ametta University of Foggia, Italy
  • Marcellino Monda University of Campania Luigi Vanvitelli, Italy
  • Antonietta Messina University of Campania Luigi Vanvitelli, Italy
  • Francesco Sessa University of Foggia, Italy
  • Chiara Porro University of Foggia, Italy
  • Daniela Pisanelli University of Foggia, Italy
  • Nunzio Di Nunno University of Salento, Italy
  • Giulio Di Mizio Magna Graecia University of Catanzaro, Italy
  • Alessio Asmundo University of Messina, Italy
  • Aurora Daniele University of Campania Luigi Vanvitelli, Italy
  • Vincenzo Cristian Francavilla Kore University of Enna, Italy


Obesity, Chronic diseases, Healthy lifestyle, Body composition, Metabolic profile


Obesity is a long-term multifactorial chronic disease, characterized by energy imbalance, due to an excess of caloric intake compared to energy expenditure and deregulation of other metabolic parameters, as, altered lipid profile, increased insulin resistance and chronic pro-inflammatory state. A healthy lifestyle, characterized by hypocaloric diet and physical activity, is important to reduce a chronic inflammation, oxidative stress and metabolic disorders typical of obesity. It is well known that the chronic inflammation state and oxidative stress are responsible for the aging and development of many diseases, such as cancer. In the light of these evidences, the aim of this study is to analyse body composition, metabolic profile and oxidative stress levels in obese patients subjected to a physical activity program before and after weight loss. We analysed the glycaemic and lipid profile, body composition such as visceral adipose tissue (VAT), fat mass (FM), and the dROMs serum levels via the Fenton's reaction. We found that in obese patients before physical activity intervention there are higher levels in dROMs serum levels, altered glycaemic and lipid profile and body composition compared to obese patients after physical activity intervention. In conclusion, the physical activity has numerous beneficial effects in obesity, modulating not only metabolic profile but also inflammatory and oxidative stress response.



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How to Cite

Polito, R., Monda, V., Ametta, A., Monda, M., Messina, A., Sessa, F., Porro, C., Pisanelli, D., Di Nunno, N., Di Mizio, G., Asmundo, A., Daniele, A., & Francavilla, V. C. (2020). Physical activity has numerous beneficial effects on metabolic and inflammatory processes. Journal of Human Sport and Exercise, 15(3proc), S815-S821. Retrieved from

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