Efficacy of pulsed electromagnetic field on hemarthrotic knee in haemophilic adolescence
Keywords:Haemophilia, Hemarthrosis, Pulsed electromagnetic field
Background: Haemophilia is a hereditary coagulopathy disease affecting males. It is characterized by musculoskeletal bleeding, leading to chronic synovitis and severe joint hemarthrosis. Objective: To determine the impact of pulsed electro- magnetic field on swelling, range of motion and muscle strength of hemarthrotic knee joints of haemophilic adolescents. Participants and Methodology: Thirty haemophilic adolescent males ranging in age between thirteen and sixteen years who fulfilled the inclusion criteria participated in this study. They were assigned randomly into two groups of equal numbers A (control) and B (study). Groups A and B received a specific program of physical therapy for sixty minutes, in addition, group A received a placebo pulsed electromagnetic field for twenty minutes, while group B received pulsed electromagnetic field for twenty minutes. The treatment program was applied three days/week for three successive months. Evaluation of knee swelling using tape measurement, range of motion using electronic goniometer and muscle strength using isokinetic dynamometer was conducted for each patient of groups A and B before and after treatment. Results: Significant improvement was observed in the post-treatment mean values of the measuring variables of groups A and B when compared with their pre-treatment results (p < .05). High significant improvement was observed in group B when comparing the post-treatment results of groups, A and B (p < .05). Conclusions: Pulsed electromagnetic field is an effective modality which can be used with the traditional methods for treatment of knee hemarthrosis in haemophilic adolescents.
Alhaosawi M.M. (2014). Guidelines of management of musculoskeletal complications of hemophilia. J Appl Hematol. 5:75-85. https://doi.org/10.4103/1658-5127.141988
Balkan C., Kavakli K., Karapinar D. (2005). Iliopsoas haemorrhage in patients with haemophilia: results from one centre. Haemophilia. 11(5):463-467. https://doi.org/10.1111/j.1365-2516.2005.01123.x
Baltzopoulos V. (2007). Isokinetic dynamometry, in: Biomechanical evaluation of movement and sport in exercise, C. Payton and R. Bartlett, ed., Routledge: London, p. 192.
Bassett C. (2002): Fundamental and Practical Aspects of Therapeutic Uses of Pulsed Electromagnetic Fields (PEMFs). Critical Reviews in Biomedical Engineering. 17,5, pp. 451-529.
Blanchette P., Rivard G., Israels S., Robinson S., Ali K., Walker I. (2004). A survey of factor prophylaxis in the Canadian haemophilia A population. Haemophilia .10:679-83. https://doi.org/10.1111/j.1365-2516.2004.01045.x
Carcao M., Hilliard P., Escobar M.A. (2015). Optimizing musculoskeletal care for patients with haemophilia. Eur J Haematol.95(suppl 81):11-21. https://doi.org/10.1111/ejh.12581
Dirnberger J., Kösters A., Müller E. (2012). Concentric and eccentric isokinetic knee extension: A reproducibility study using the IsoMed 2000-dynamometer. Isokinet Exerc Sci. 20. 31-35. https://doi.org/10.3233/IES-2012-0437
Eid A. and Aly M. (2015): LASER versus electromagnetic field in treatment of hemarthrosis in children with hemophilia. Lasers Med Sci 30, 2179-2187. https://doi.org/10.1007/s10103-015-1794-6
Gomis M., Querol F., Gallach J.E., González L.M., Aznar J.A (2009). Exercise and sport in the treatment of haemophilic patients: a systematic review. Haemophilia. 15: 43-54. https://doi.org/10.1111/j.1365-2516.2008.01867.x
Gringeri A., Ewenstein B., Reininger A. (2014). The burden of bleeding in haemophilia: is one bleed too many? Haemophilia. 20: 459-463. https://doi.org/10.1111/hae.12375
Hinman R., Ford J., Hey H. (2002): Effects of static magnets on chronic knee pain and physical function: a double-blind study. Alternat Ther Health Med;8:50-5.
Jacobson J., Gorman R., Yamanashi W., Saxena B., Clayton L (2001): "Low amplitude, extremely low frequency magnetic field for the treatment of osteoarthritic knee" A double blind clinical study. Altern Ther Health Med., 7(5): 54-64.
Knobe K. and Berntorp E. (2011). Haemophilia and joint disease: Pathophysiology, evaluation, and management. Journal of Comorbidity. 1. https://doi.org/10.15256/joc.2011.1.2
Lissauer T. and Clayden G. (2007). Illustrated textbook of paediatrics. 4th ed. Toronto: Elsevier.
Markov M. and Colbert A. (2000). Magnetic and Electromagnetic Field Therapy. J. Back Musclou Rehabil. 80: 545-550.
McCrae R. (1989). Knee joint examination. In Clinical Orthopedic Examination; Chapter II; pp 171-208.
Parhampour B., Torkaman G., Hoorfar H., Hedayati M., Ravanbod R. (2014) Effects of the short-term resistance training and pulsed electromagnetic fields on bone metabolism and joint function in severe haemophilia A patients with osteoporosis: a randomized controlled trial. Clin Rehabil 28(5):440-450. https://doi.org/10.1177/0269215513505299
Quittan M., Schuhfried O., Wiesinberg G., Moser V. (2004) Clinical effectiveness of magnetic field therapy. A review of literature. Acta Med Austriaca 27(3):61-68.
Ramasamy S., Kalaivani G., Narayana R. (2008). Low Frequency and Low Intensity Pulsed Electromagnetic Field Exerts Anti-Inflammatory Effect Through Restoration of Plasma Membrane Atpase Activity. Life Sciences (80) 2403-2410. https://doi.org/10.1016/j.lfs.2007.03.019
Rodriguez-Merchan E.C. (2008). Articular bleeding (hemarthrosis) in hemophilia. An orthopedist's point of view. In: Schulman S, editor. Treatment of Hemophilia Monographs No. 23, April 2008. Montreal: World Federation of Hemophilia. Retrieved from: http://www1.wfh.org/publication/files/pdf-1155.pdf [Last accessed Sep 10, 2021].
Ryczko M. and Persinger M. (2002): Increased analgesia to thermal stimuli in rates after brief exposure to complex pulsed 1 micro tesla magnetic field. perceptual and motor skills., 95:592-598. https://doi.org/10.2466/pms.2002.95.2.592
Santos A. (2011). Genetic and immunologic aspects related to the development of inhibitors in haemophilia A and B. Campina. 189:1-189.
Segal N., Huston J., Fuchs H., Holocomb R., Mclean M. (1999). Efficacy of static magnetic device against knee pain associated with inflammatory arthritis. J. Clin. Rheumatol., 5:302-304. https://doi.org/10.1097/00124743-199910000-00016
Srivastava A., Brewer A.K., Mauser-Bunschoten E.P., Key N.S., Kitchen S,. Llinas A. (2013). Treatment Guidelines Working Group on Behalf of The World Federation of Hemophilia. Guidelines for the management of hemophilia. Haemophilia. Jan;19(1): e1-47. https://doi.org/10.1111/j.1365-2516.2012.02909.x
Tiktinsky R., Chen L., Narayan P. (2010).Electrotherapy: yesterday, today and tomorrow. Hemophilia 16:126-131. https://doi.org/10.1111/j.1365-2516.2010.02310.x
Trock D. (2000) Electromagnetic field and magnets investigational treatment for musculoskeletal disorders. Rheum. Dis. Clin. North. Am. 26(1): 51-62.
Trock D.H., Bollet A.J, Dyer P.H., Fielding L.P., Minger W.K., Markoll R. (1993). A Double-blind trial of the clinical effects of pulsed electromagnetic fields in osteoarthritis. J Rheumatol 20(3):456-460.
Vincenzi F., Targa M., Corciulo C., Gessi S., Merighi S., Setti S., Cadossi R., Goldring M.B., Borea P.A., Varani K. (2013). Pulsed electromagnetic fields increased the anti-inflammatory effect of A2A and A3 adenosine receptors in human T/C-28a2 chondrocytes and HFOB 1.19 osteoblasts. PLoS One 8(5): e65561. https://doi.org/10.1371/journal.pone.0065561
Weinberger A., Nyska A., Giler S. (1996): Treatment of Experimental Inflammatory Sinuvitis with Magnetic Field. J. Med. Scr. 32:1197-201.
Wilk K. (1990): Muscle strength testing: Instrumented and non-instrumented Systems. New York, Chruchill Livingstone, pp. 60-63, 123-150.
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