Use of nutritional supplement to improve performance in professional soccer players: A case report


  • Giuseppe Messina University of Palermo, Italy
  • Vincenzo Cristian Francavilla University of Enna “Kore”, Italy
  • Valerio Giustino University of Palermo, Italy
  • Omar Mingrino University of Enna “Kore”, Italy
  • Federico Genovesi Manchester City FC, United Kingdom
  • Alessandra Amato University of Palermo, Italy
  • Patrizia Proia University of Palermo, Italy



Soccer, Supplementation, Physical exercise, Muscle, Nutrition


The aim of the study was to investigate the intake percentage and the satisfaction level of some nutritional supplements used by professional soccer players. Twenty-nine professional soccer players (age: 24.6 ± 5.2 years, body weight: 79.2 ± 4.9 kg, body height: 1.83 ± 0.05 m) belonging to a team of Serie A were interviewed on: frequency of use, tolerability, and acceptance of the supplements (creatine, β-alanine, whey protein, nitrates, vitamin D3, caffeine) proposed by the nutritionist team. This survey revealed a great inter-individual variability on the intake of the proposed supplements. All respondents (n = 29) said they take cholecalciferol (vitamin D3), 17 out of 29 creatine, 14 out of 29 whey protein, and 10 out of 29 dietary nitrates. No participants declared to assume β-alanine or caffeine anhydrous. Cholecalciferol resulted the most accepted supplement, followed by creatine and whey protein. Study participants prefer to take dietary nitrates through the consumption of vegetable juices, primarily from fennel and celery juice, and only two out of twenty-nine regularly taking concentrated beet juice. Since none of the twenty-nine participants interviewed uses β-alanine and caffeine in anhydrous form, the daily contribution of caffeine is mainly guaranteed by the consumption of coffee.


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Bailey, S. J., Winyard, P., Vanhatalo, A., Blackwell, J. R., Dimenna, F. J., Wilkerson, D. P., . . . Jones, A. M. (2009). Dietary nitrate supplementation reduces the O2 cost of low-intensity exercise and enhances tolerance to high-intensity exercise in humans. J Appl Physiol (1985), 107(4), 1144-1155.

Beelen, M., Kranenburg, J., Senden, J. M., Kuipers, H., & Loon, L. J. (2012). Impact of caffeine and protein on postexercise muscle glycogen synthesis. Med Sci Sports Exerc, 44(4), 692-700.

Behrouzi, A., Hejazi, H., Kamali, A., & Hadi, H. (2018). Investigation of the outcome of patients with hip fractures using vitamin D3. Eur J Transl Myol, 28(3), 288-293.

Bianco, A., Thomas, E., Bellafiore, M., Martines, F., Messina, G., Battaglia, G., . . . Palma, A. (2015). Mediterranean diet and dietary protein supplementation as possible predicting variables of weight management: An update of the protein project. Acta Medica Mediterranea, 31, 1265-1270.

Casey, A., Constantin-Teodosiu, D., Howell, S., Hultman, E., & Greenhaff, P. L. (1996). Creatine ingestion favorably affects performance and muscle metabolism during maximal exercise in humans. Am J Physiol, 271(1 Pt 1), E31-37.

Close, G. L., Russell, J., Cobley, J. N., Owens, D. J., Wilson, G., Gregson, W., . . . Morton, J. P. (2013). Assessment of vitamin D concentration in non-supplemented professional athletes and healthy adults during the winter months in the UK: implications for skeletal muscle function. J Sports Sci, 31(4), 344-353.

Drake, C., Roehrs, T., Shambroom, J., & Roth, T. (2013). Caffeine effects on sleep taken 0, 3, or 6 hours before going to bed. J Clin Sleep Med, 9(11), 1195-1200.

Francavilla, V. C., Bongiovanni, T., Genovesi, F., Minafra, P., & Francavilla, G. (2015). La Bia segmentale: metodica utile per il follow-up di una lesione muscolare? Un caso clinico. Med Sport, 68(2), 323-334.

Francavilla, V. C., Bongiovanni, T., Todaro, L., Di Pietro, V., & Francavilla, G. (2017). Probiotic supplements and athletic performance: a review of the literature. Med Sport, 70(2), 247-259.

Goldstein, E. R., Ziegenfuss, T., Kalman, D., Kreider, R., Campbell, B., Wilborn, C., . . . Antonio, J. (2010). International society of sports nutrition position stand: caffeine and performance. J Int Soc Sports Nutr, 7(1), 5.

Graham, T. E., & Spriet, L. L. (1995). Metabolic, catecholamine, and exercise performance responses to various doses of caffeine. J Appl Physiol (1985), 78(3), 867-874.

Haider, G., & Folland, J. P. (2014). Nitrate supplementation enhances the contractile properties of human skeletal muscle. Med Sci Sports Exerc, 46(12), 2234-2243.

Integratori alimentari e Linee guida ministeriali (LGM). (2002). Retrieved from

Jones, A. M. (2014). Dietary nitrate supplementation and exercise performance. Sports Med, 44 Suppl 1, S35-45.

Krustrup, P., Mohr, M., Steensberg, A., Bencke, J., Kjaer, M., & Bangsbo, J. (2006). Muscle and blood metabolites during a soccer game: implications for sprint performance. Med Sci Sports Exerc, 38(6), 1165-1174.

Lansley, K. E., Winyard, P. G., Fulford, J., Vanhatalo, A., Bailey, S. J., Blackwell, J. R., . . . Jones, A. M. (2011). Dietary nitrate supplementation reduces the O2 cost of walking and running: a placebo-controlled study. J Appl Physiol (1985), 110(3), 591-600.

Maridakis, V., Herring, M. P., & O'Connor, P. J. (2009). Sensitivity to change in cognitive performance and mood measures of energy and fatigue in response to differing doses of caffeine or breakfast. Int J Neurosci, 119(7), 975-994.

Mazzeo, F., Motti, M. L., Messina, G., Monda, V., Ascione, A., Tafuri, D., . . . Monda, M. (2013). Use of nutritional supplements among south Italian students of Physical Training and Sport University. Curr Top Toxicol, 9, 21-26.

Messina, G., Zannella, C., Monda, V., Dato, A., Liccardo, D., De Blasio, S., . . . Monda, M. (2015). The Beneficial Effects of Coffee in Human Nutrition. Biol Med, 7(4).

Mohr, M., Nielsen, J. J., & Bangsbo, J. (2011). Caffeine intake improves intense intermittent exercise performance and reduces muscle interstitial potassium accumulation. J Appl Physiol (1985), 111(5), 1372-1379.

Morton, J. P., Iqbal, Z., Drust, B., Burgess, D., Close, G. L., & Brukner, P. D. (2012). Seasonal variation in vitamin D status in professional soccer players of the English Premier League. Appl Physiol Nutr Metab, 37(4), 798-802.

Nutrition for football: the FIFA/F-MARC Consensus Conference. (2006). J Sports Sci, 24(7), 663-664.

Proia, P., Amato, A., Contro, V., Monaco, A. L., Brusa, J., Brighina, F., & Messina, G. (2019). Relevance of lactate level detection in migrane and fibromyalgia. Eur J Transl Myol, 29(2), 8202.

Vanhatalo, A., Bailey, S. J., Blackwell, J. R., DiMenna, F. J., Pavey, T. G., Wilkerson, D. P., . . . Jones, A. M. (2010). Acute and chronic effects of dietary nitrate supplementation on blood pressure and the physiological responses to moderate-intensity and incremental exercise. Am J Physiol Regul Integr Comp Physiol, 299(4), R1121-1131.

Webb, A. R., & Holick, M. F. (1988). The role of sunlight in the cutaneous production of vitamin D3. Annu Rev Nutr, 8, 375-399.

Wyss, M., & Kaddurah-Daouk, R. (2000). Creatine and creatinine metabolism. Physiol Rev, 80(3), 1107-1213.


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How to Cite

Messina, G., Francavilla, V. C., Giustino, V., Mingrino, O., Genovesi, F., Amato, A., & Proia, P. (2020). Use of nutritional supplement to improve performance in professional soccer players: A case report. Journal of Human Sport and Exercise, 15(2proc), S289-S298.

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