Circadian rhythms, physical activity and longevity
Keywords:
Circadian rhythms, Human health, Physical activity, Longevity, Training activityAbstract
Human health implies complex mechanisms and involves diseases prevention aimed at ensuring a psycho-physical wellbeing homoeostasis. The search for longevity can be related to the slowdown in aging, and psycho-physical wellbeing is often related to the lifestyle, mainly to the human physical activity and nutrition. Circadian rhythms are processes that affect the behaviour, physiology and metabolism of mammals across cyclic periods of 24 hours. These rhythms are regulated by multiple physiological systems, whose key elements are the alternation between light and dark and between food consumption and periods of fasting. Therefore, during evolution, a constant adaptation to natural rhythms by humans has been established towards the surrounding environment determining periods of food consumption and periods of fasting coinciding with rest. Recent sociological surveys have shown that there is a slight increase in the number of people who devote themselves to a constant physical/sport activity, but this is an ephemeral percentage compared to the dramatic increase in the incidence of diseases related to aging such as obesity and diabetes, easily preventable with healthy lifestyles. Therefore, the connection between circadian rhythms, physical activity and lifestyles represents an important feature involved in human longevity. Here, a survive of the biological mechanisms, implied in this behaviour, is presented.Downloads
References
Adornetto A, Pagliara V, Renzo GD, Arcone R. (2013) Polychlorinated biphenyls impair dibutyryl cAMP-induced astrocytic differentiation in rat C6 glial cell line. FEBS Open Bio 3, 459-466.
https://doi.org/10.1016/j.fob.2013.10.008
Baehr EK, Eastman CI, Revelle W, Olson SH, Wolfe LF, Zee PC. (2003) Circadian phase-shifting effects of nocturnal exercise in older compared with young adults. Am. J. Physiol. Regul. Integr. Comp. Physiol. 284, 1542-1550. https://doi.org/10.1152/ajpregu.00761.2002
Bollinger T, Schibler U. (2014) Circadian rhythms - from genes to physiology and disease. Swiss Med. Wkly 144, w13984. https://doi.org/10.4414/smw.2014.13984
Davis S, Mirick DK. (2006) Circadian disruption, shift work and the risk of cancer: a summary of the evidence and studies in Seattle. Cancer Causes Control 17, 539–545. https://doi.org/10.1007/s10552-005-9010-9
de Laurentiis A, Gaspari M, Palmieri C, Falcone C, Iaccino E, Fiume G, Massa O, Masullo M, Tuccillo FM, Roveda L, Prati U, Fierro O, Cozzolino I, Troncone G, Tassone P, Scala G, Quinto I. (2011) Mass spectrometry-based identification of the tumor antigen UN1 as the transmembrane CD43 sialoglycoprotein. Mol. Cell. Proteom. 10, M111.007898. https://doi.org/10.1074/mcp.m111.007898
Froy O. (2018) Circadian rhythms, nutrition and implications for longevity in urban environments. Proc. Nutr. Soc. 77, 216-222. https://doi.org/10.1017/s0029665117003962
Gillette MU, Tischkau SA. (1999) Suprachiasmatic nucleus: the brain's circadian clock. Recent Prog. Horm. Res. 54, 33-58.
Hanahan D. and Weinberg, RA. (2011) Hallmarks of cancer: the next generation. Cell 144, 646-674. https://doi.org/10.1016/j.cell.2011.02.013
Harrington ME. (2012) Exercise strengthens circadian cloks. J. Physiol. 590, 5929-5929. https://doi.org/10.1113/jphysiol.2012.245308
Heden TD, Kanaley JA. (2019) Syncing Exercise With Meals and Circadian Clocks. Exerc. Sport Sci. Rev. 47, 22-28. https://doi.org/10.1249/jes.0000000000000172
Hood S, Amir S. (2017) The aging clock: circadian rhythms and later life. J. Clin. Invest. 127, 437-446. https://doi.org/10.1172/jci90328
Jackson EL, Willis N, Mercer K, Bronson RT, Crowley D, Montoya R, Jacks T, Tuveson DA. (2001) Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras. Genes Dev. 15, 3243-3248. https://doi.org/10.1101/gad.943001
Ko CH, Takahashi JS. (2006) Molecular components of the mammalian circadian clock. Hum. Mol. Genet. 15, R271-R277. https://doi.org/10.1093/hmg/ddl207
Liguori G, Gallé F, Valeriani F, Romano Spica V. (2015) The role of the hygienist in prevention and health promotion through physical activity: the contribute of the Working Group "Movement Sciences for Health" of the Italian Society of Hygiene, Ann. Ig. 27, 11-15.
Liu F, Chang HC. (2017) Physiological links of circadian clock and biological clock of aging. Protein Cell. 8, 477-488. https://doi.org/10.1007/s13238-016-0366-2
Masri S, Sassone-Corsi P. (2018) The emerging link between cancer, metabolism, and circadian rhythms. Nat. Med. 24, 1795-1803. https://doi.org/10.1038/s41591-018-0271-8
Montesano P, Mazzeo F. (2019) Sports Activities in Obese Teenagers Improve Social Inclusion and Health. Sport Mont., 17, 55-60. https://doi.org/10.26773/smj.190210
Oike H. (2017) Modulation of circadian clocks by nutrients and food factors. Biosci. Biotechnol. Biochem. 81, 863-870.
Pagliara V, Adornetto A, Mammì M, Masullo M, Sarnataro D, Pietropaolo C, Arcone R. (2014) Protease Nexin-1 affects the migration and invasion of C6 glioma cells through the regulation of urokinase Plasminogen Activator and Matrix Metalloproteinase-9/2. Biochim. Biophys. Acta 1843, 2631-2644. https://doi.org/10.1016/j.bbamcr.2014.07.008
Panda S, Antoch MP, Miller BH, Su AI, Schook AB, Straume M, Schultz PG, Kay SA, Takahashi JS, Hogenesch JB. (2002) Coordinated transcription of key pathways in the mouse by the circadian clock. Cell 109, 307-20. https://doi.org/10.1016/s0092-8674(02)00722-5
Panda S. (2016) Circadian physiology of metabolism. Science 354, 1008-1015.
Papagiannakopoulos T, Bauer MR, Davidson SM, Heimann M, Subbaraj L, Bhutkar A, Bartlebaugh J, Vander Heiden MG, Jacks T. (2016) Circadian rhythm disruption promotes lung tumorigenesis. Cell. Metab. 24, 324-331. https://doi.org/10.1016/j.cmet.2016.07.001
Qureshi IA, Mehler MF. (2014) Epigenetics of sleep and chronobiology. Curr. Neurol. Neurosci. Rep. 14, 432. https://doi.org/10.1007/s11910-013-0432-6
Rosbash M. (1995) Molecular control of circadian rhythms. Curr. Opin. Genet. Dev. 5, 662-668.
Saint Onge JM, Krueger PM. (2017) Health Lifestyle Behaviors among U.S. Adults. SSM Popul. Health. 3, 89-98. https://doi.org/10.1016/j.ssmph.2016.12.009
Schibler U, Ripperger J, Brown SA. (2003) Peripheral circadian oscillators in mammals: time and food. J. Biol. Rhythms 18, 250-260. https://doi.org/10.1177/0748730403018003007
Sellami M, Bragazzi NL, Slimani M, Hayes L, Jabbour G, De Giorgio A, Dugué B. (2019) The Effect of Exercise on Glucoregulatory Hormones: A Countermeasure to Human Aging: Insights from a Comprehensive Review of the Literature. Int. J. Environ. Res. Public Health 16, pii: E1709. https://doi.org/10.3390/ijerph16101709
Sollars PJ, Pickard GE. (2015) The Neurobiology of Circadian Rhythms. Psychiatr. Clin. North Am. 38, 645-665.
Spann SJ, Ottinger MA (2018) Longevity, Metabolic Disease, and Community Health. Prog. Mol. Biol. Transl. Sci. 155, 1-9.
Stenvers DJ, Scheer FAJL, Schrauwen P, la Fleur SE, Kalsbeek A. (2019) Circadian clocks and insulin resistance. Nat. Rev. Endocrinol. 15, 75-89. https://doi.org/10.1038/s41574-018-0122-1
Wu X, Chen L, Zeb F, Li C, Jiang P, Chen A, Xu C, Haq IU, Feng Q. (2019) Clock-Bmal1 mediates MMP9 induction in acrolein-promoted atherosclerosis associated with gut microbiota regulation. Environ. Pollut. 252, 1455-1463. https://doi.org/10.1016/j.envpol.2019.06.042
Wyatt SB, Winters KP, Dubbert PM. (2006) Overweight and obesity: prevalence, consequences, and causes of a growing public health problem. Am. J. Med. Sci. 331,166-74. https://doi.org/10.1007/s13679-015-0169-4
Yokoyama Y, Sasaki M, Sato K. (2019) Nutrition intake among the Japanese elderly: an intergenerational comparison based on National Health and Nutrition Survey scores. Ann. Hum. Biol., in press. https://doi.org/10.1080/03014460.2019.1662943
Youngstedt SD, Kripke DF, and Elliott JA. (2002) Circadian phase- delaying effects of bright light alone and combined with exercise in humans. Am. J. Physiol. Regul. Integr. Comp. Physiol. 282, R259-R262. https://doi.org/10.1152/ajpregu.00473.2001
Zwighaft Z, Aviram R, Shalev M, Rousso-Noori L, Kraut-Cohen J, Golik M, Brandis A, Reinke H, Aharoni A, Kahana C, Asher G. (2015) Circadian Clock Control by Polyamine Levels through a Mechanism that Declines with Age. Cell Metab. 22, 874-885. https://doi.org/10.1016/j.cmet.2015.09.011
Downloads
Statistics
Published
How to Cite
Issue
Section
License
Copyright (c) 2020 Journal of Human Sport and Exercise
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Each author warrants that his or her submission to the Work is original and that he or she has full power to enter into this agreement. Neither this Work nor a similar work has been published elsewhere in any language nor shall be submitted for publication elsewhere while under consideration by JHSE. Each author also accepts that the JHSE will not be held legally responsible for any claims of compensation.
Authors wishing to include figures or text passages that have already been published elsewhere are required to obtain permission from the copyright holder(s) and to include evidence that such permission has been granted when submitting their papers. Any material received without such evidence will be assumed to originate from the authors.
Please include at the end of the acknowledgements a declaration that the experiments comply with the current laws of the country in which they were performed. The editors reserve the right to reject manuscripts that do not comply with the abovementioned requirements. The author(s) will be held responsible for false statements or failure to fulfill the above-mentioned requirements.
This title is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International license (CC BY-NC-ND 4.0).
You are free to share, copy and redistribute the material in any medium or format. The licensor cannot revoke these freedoms as long as you follow the license terms under the following terms:
Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
NonCommercial — You may not use the material for commercial purposes.
NoDerivatives — If you remix, transform, or build upon the material, you may not distribute the modified material.
No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
Notices:
You do not have to comply with the license for elements of the material in the public domain or where your use is permitted by an applicable exception or limitation.
No warranties are given. The license may not give you all of the permissions necessary for your intended use. For example, other rights such as publicity, privacy, or moral rights may limit how you use the material.
Transfer of Copyright
In consideration of JHSE’s publication of the Work, the authors hereby transfer, assign, and otherwise convey all copyright ownership worldwide, in all languages, and in all forms of media now or hereafter known, including electronic media such as CD-ROM, Internet, and Intranet, to JHSE. If JHSE should decide for any reason not to publish an author’s submission to the Work, JHSE shall give prompt notice of its decision to the corresponding author, this agreement shall terminate, and neither the author nor JHSE shall be under any further liability or obligation.
Each author certifies that he or she has no commercial associations (e.g., consultancies, stock ownership, equity interest, patent/licensing arrangements, etc.) that might pose a conflict of interest in connection with the submitted article, except as disclosed on a separate attachment. All funding sources supporting the Work and all institutional or corporate affiliations of the authors are acknowledged in a footnote in the Work.
Each author certifies that his or her institution has approved the protocol for any investigation involving humans or animals and that all experimentation was conducted in conformity with ethical and humane principles of research.
Competing Interests
Biomedical journals typically require authors and reviewers to declare if they have any competing interests with regard to their research.
JHSE require authors to agree to Copyright Notice as part of the submission process.
